downstream process specialist à Reinach

Lucie Nasshan, Bâle Professionals Health Care & Life Sciences
type d'emploi
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job details

reinach, argovie
Life Sciences
type d'emploi
lucie nasshan, bâle professionals health care & life sciences
058 201 55 50
postuler >

description du poste

Randstad Professionals is currently looking for a Downstream process specialist for a permanent position for one of our client in the Basel area.. This contract is an unique opportunity to join an innovative company in the pharma industry.

As Process Engineer, you will be a key member of our Process Team, responsible for downstream process (DSP) development and commercial scale up of our fermentation-based processes. You will be involved in both, lab and pilot plant processing trials and testing, optimization of key process operating parameters from the lab to pilot plant scale, and process transfer to manufacturing facilities.

Your key responsibilities will include:

  • Perform downstream process development and purification/separation techniques at benchtop-scale

  • Optimizes processes for improved operability, cost reduction and downstream process improvement

  • Support the transfer and scale up of commercial manufacturing processes to CMOs Developing mass, utility and energy balances and defining utility consumption and generation requirements

  • Leading the technical development of process narratives, block flow diagrams (BFDs), process flow diagrams (PFDs) and P&IDs

  • Assist in the development of manufacturing documentation such as process descriptions, batch records and SOPs

  • Scale benchtop-scale downstream processes to pilot-scale and industrial-scale

  • Develop an overall process understanding and provide suggestions/feedback to upstream process team

  • Provide technical support and troubleshooting assistance for commercial scale operations

The following skills are required:

  • M.S. in Chemical Engineering, Biochemistry or related disciplines, with a minimum of 4+ years of working experience in an industrial setting, ideally including interaction with industrial/commercial partners

  • Hands-on experience with industrial scale bioprocessing recovery equipment

  • Demonstrated capability to participate in multidisciplinary teams

  • Experience in successful execution and management of process technical transfer Experienced in downstream/purification process development and scale up through process validation and technology transfer

  • Thorough knowledge of ion exchange chromatography as well as membrane filtration applications for downstream processing

  • Hands-on experience with common large scale DSP equipment (centrifugation, chromatography and filtration skids)

  • Good understanding of microbial fermentation processes would be a plus

  • Hands-on experience and understanding of sampling and analytical chemistry (HPLC and GC) would be a plus

  • Good understanding of principles of organic synthesis and catalysis is a plus Excellent written and oral communication skills

  • Very good command of English

  • Ability to travel (CMO support) up to 20%

If you are interested for this great role, don't hesitate to send your application with a CV in English or to contact me directly.  I am looking forward to sharing informations with you.