Protein Conjugation Specialist in Barbengo / Lugano

veröffentlicht
Kontakt
Mayank Chaubey, Basel Professionals Health Care & Life Sciences
Jobtyp
Festanstellung
jetzt bewerben

job details

veröffentlicht
Ort
Barbengo / Lugano
Sektor
Life Sciences
Jobtyp
Festanstellung
Referenznummer
10477
Kontakt
Mayank Chaubey, Basel Professionals Health Care & Life Sciences
Telefon
058 201 55 50
jetzt bewerben

Stellenbeschreibung

Our client a privately held company located in Lugano, Switzerland, specializing in the development and manufacture of both chemical and biological APIs for its partners world-wide is currently looking for

Protein Conjugation Specialist

The talented and highly motivated scientist is expected to integrate in R&D team dedicated to the development of therapeutic protein conjugates.

Role description:

  1. Synthesis of protein-drug conjugations, including familiarization, optimization and process development.
  2. Purification of protein conjugates using chromatographic FPLC systems (size exclusion, affinity, HIC) and filtration technologies (ultrafiltration and diafiltration).
  3. Analysis and characterization of protein conjugates using the common analytical methodologies (HPLC, UV/Vis, electrophoresis, LC-MS and other relevant techniques).
  4. Perform scale-up of conjugation processes according to the cGMP.
  5. Support the analytical team for method development.

Requirements:

  1. MSc, PhD or relevant experience in Biochemistry, Chemistry or a related field.
  2. Proven experience in conjugation of proteins including antibodies and relative fragments to cytotoxic payloads, peptides, toxins.
  3. Experience in protein purification with common FPLC instrumentation.
  4. Practical experience using filtration technologies such as TFF.
  5. Prior experience in bioconjugate characterization using common analytical techniques.
  6. Knowledge of the cGMP guidelines both Theoretical and Practical.
  7. Capable of working independently and learn/optimize new techniques.
  8. Team player with strong communication skills and ability to solve problems.

If this interests you then, 

We are looking forward to receiving within your application:

  • your CV in English

  • latest Work Certificates

  • your Motivation Letter  

  • the date of your availability

Apply now to be considered – Good to know you!

For more information and your application, please contact:

Mayank Chaubey, PhD

Consultant Randstad Professionals Healthcare & Life-science

mayank.chaubey@randstad.ch