Research Associate Mass Spectrometry (m/f/d)

The MS team within the Lead Discovery department is using a wide range of mass spectrometry based approaches for high throughput screening for hit finding, profiling of lead compounds and discovering drug candidate target interaction using cell free assays, cellular systems and tissue samples. This lab based position will primarily focus on deciphering drug candidate target interaction by quantifying endogenous metabolites, lipids, and characterizing protein modification in cellular systems and tissue.


General Information:

• Start date: ASAP
• Latest Start Date: 01.10.2025
• Planned duration: 9 months
• Extension: very likely
• Workplace: Basel
• Workload: 100%
• Home Office: not possible
• Working hours: Standard

Tasks & Responsibilities: 
 

• In this lab based role, you will implement, optimize and use LC-MS workflows for metabolites, lipids and proteins, including sample preparation, measurement, data analysis and reporting.
• You will prepare and analyze samples from cell culture and tissue using mass spectrometry.
• You present and discuss your data and findings with colleagues.
• You work collaboratively with your colleagues to contribute to general laboratory operations within the MS team, including instrument maintenance, and troubleshooting.

Must Haves:
 

• You completed an apprenticeship, or possess a BS or MS degree in a relevant field
• Min 3 years. experience in the pharmaceutical or life science field.
• You have hands-on experience with LC and MS equipment like Triple Quadrupole and/or ToF type instruments, including method development, routine analysis and troubleshooting of instrumentation.
• You bring experience with sample preparation techniques such as homogenization of tissue and cells, extraction or related approaches.
• Fluent in written and verbal English

Nice to Have:
 

• Experience with analysing recombinant proteins (like intact mass, peptide mapping), proteomics, metabolomics or lipidomics workflows